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Article

Reduced serum progranulin level might be associated with Parkinson's disease risk.

European journal of neurology - 1 Dec 2013

Mateo I, González-Aramburu I, Pozueta A, Vázquez-Higuera J L, Rodríguez-Rodríguez E, Sánchez-Juan P, Calero M, Dobato J L, Infante J, Berciano J, Combarros O

Abstract excerpt

BACKGROUND AND PURPOSE: Common genetic variants (rs5848 and rs646776) have been reported as regulators of blood progranulin (GRN) levels in healthy individuals. METHODS: To assess the influence of rs5848 and rs646776 polymorphisms in both serum GRN level and risk for common neurodegenerative diseases, we studied 304 patients with Parkinson's disease (PD), 217 individuals with Alzheimer's disease, 131 subjects...

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Share to Aged
Share to Aged, 80 and over
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Intercellular Signaling Peptides and Proteins
Share to Parkinson Disease
Share to Polymorphism, Single Nucleotide
Share to Progranulins

Source

Identifiers

PMID: 23398167
DOI: 10.1111/ene.12090

Genes

GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Reduced serum progranulin level might be associated with Parkinson's disease risk.PMID 23398167Read ↗

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Role of progranulin as a biomarker for Alzheimer's disease.Semantic proximity Read ↗

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