Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell and molecular biology of epidermal growth factor receptor.

International review of cell and molecular biology - 1 Jan 2014

Ceresa Brian P, Peterson Joanne L

Abstract excerpt

The epidermal growth factor receptor (EGFR) has been one of the most intensely studied cell surface receptors due to its well-established roles in developmental biology, tissue homeostasis, and cancer biology. The EGFR has been critical for creating paradigms for numerous aspects of cell biology, such as ligand binding, signal transduction, and membrane trafficking. Despite this history of discovery, there is a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ErbB Receptors
Share to Ligands
Share to Phosphorylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Conformation

Share to Protein Multimerization

Share to Protein Transport

Share to Structure-Activity Relationship

Share to Ubiquitination

Source

Identifiers

PMID: 25376492
DOI: 10.1016/B978-0-12-800177-6.00005-0

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell and molecular biology of epidermal growth factor receptor.PMID 25376492Read ↗

Epidermal growth factor receptor: Role in human cancerSemantic proximity Read ↗

The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification.Semantic proximity Read ↗

The epidermal growth factor receptor familySemantic proximity Read ↗

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor familySemantic proximity Read ↗

Mechanisms for oncogenic activation of the epidermal growth factor receptor.Semantic proximity Read ↗

Therapeutic targeting of the epidermal growth factor receptor in human cancer.Semantic proximity Read ↗

The epidermal growth factor receptor pathway: a model for targeted therapy.Semantic proximity Read ↗

Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis.Semantic proximity Read ↗

Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials.Semantic proximity Read ↗

Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future ResearchSemantic proximity Read ↗

EGFR mutations and abnormal trafficking in cancers.Semantic proximity Read ↗

Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing Both Kinase-Dependent and Kinase-Independent Functions of the Receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.