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Tumour viruses and innate immunity

11 Sept 2017

Abstract excerpt

Host cells sense viral infection through pattern recognition receptors (PRRs), which detect pathogen-associated molecular patterns (PAMPs) and stimulate an innate immune response. PRRs are localized to several different cellular compartments and are stimulated by viral proteins and nucleic acids. PRR activation initiates signal transduction events that ultimately result in an inflammatory response. Human tumour...

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PMID: 28893934
DOI: 10.1098/rstb.2016.0267

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