Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Panobinostat in adults with H3 K27M-mutant diffuse midline glioma: a single-center experience.

Journal of neuro-oncology - 1 Mar 2022

Neth Bryan J, Balakrishnan Samantha N, Carabenciov Ivan D, Uhm Joon H, Daniels David J, Kizilbash Sani H, Ruff Michael W

Abstract excerpt

INTRODUCTION: Diffuse midline gliomas (DMG) with the H3 K27M-mutation are a well-described entity with most DMG harboring this mutation, with notable heterogeneity in adults. No therapy has been proven to improve survival in this tumor type. Panobinostat is a histone deacetylase inhibitor that may have therapeutic benefit. METHODS: We report our retrospective experience with use of panobinostat in adults...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Glioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Mutation

Share to Young Adult

Source

Identifiers

PMID: 35076860
DOI: 10.1007/s11060-022-03950-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Panobinostat in adults with H3 K27M-mutant diffuse midline glioma: a single-center experience.PMID 35076860Read ↗

Adult diffuse midline gliomas H3 K27-altered: review of a redefined entity.Semantic proximity Read ↗

Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adultsSemantic proximity Read ↗

Comparative analysis of clinical characteristics and prognostic factors in adult and pediatric patients with H3K27M-mutant diffuse midline glioma.Semantic proximity Read ↗

Survival analysis of adult midline-located gliomas and diffuse midline gliomas: beyond the H3K27 mutation paradigm.Semantic proximity Read ↗

Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location.Semantic proximity Read ↗

Characteristics of H3K27M-mutant diffuse gliomas with a non-midline locationSemantic proximity Read ↗

H3K27-Altered Diffuse Midline Glioma of the Brainstem: From Molecular Mechanisms to Targeted Interventions.Semantic proximity Read ↗

Prognostic Indicators and Treatment Strategies for Diffuse Midline Glioma: a Systematic ReviewSemantic proximity Read ↗

Bench-to-bedside investigations of H3 K27-altered diffuse midline glioma: drug targets and potential pharmacotherapies.Semantic proximity Read ↗

Diffuse midline glioma treated with epigenetic agent-based immunotherapySemantic proximity Read ↗

H3G34-Mutant Gliomas—A Review of Molecular Pathogenesis and Therapeutic OptionsSemantic proximity Read ↗

Prognostic Indicators for H3K27M-Mutant Diffuse Midline Glioma: A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.