Article
Genome-Wide Association Analyses Identify CATSPERE as a Mediator of Colorectal Cancer Susceptibility and Progression.
Cancer research - 15 Mar 2022
Meng Yixuan, Du Mulong, Gu Dongying, Li Chen, Li Shuwei, Zhang Qiuyi, Ben Shuai, Zhu Qiuyuan, Xin Junyi, Zhang Zhengdong, Hu Zhibin, Shen Hongbing, Jiang Kewei, Wang Meilin
Abstract excerpt
Genome-wide association studies (GWAS) have revealed numerous genetic loci associated with colorectal cancer risk, but the mechanisms underlying these loci have not been comprehensively elucidated. In this study, we performed a GWAS meta-analysis with a two-stage replication strategy by combining eight colorectal cancer cohorts encompassing 7,186 cases and 8,512 controls in Chinese populations, accompanied by an...
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