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Article

Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer.

PloS one - 1 Jan 2000

Sangster Ami G, Gooding Robert J, Garven Andrew, Ghaedi Hamid, Berman David M, Davey Scott K

Abstract excerpt

Muscle Invasive bladder cancer is known to have an abundance of mutations, particularly in DNA damage response and chromatin modification genes. The role of these mutations in the development and progression of the disease is not well understood. However, a mutually exclusive mutation pattern between gene pairs could suggest gene mutations of significance. For example, a mutually exclusive mutation pattern could...

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Identifiers

PMID: 35073341
DOI: 10.1371/journal.pone.0259992
PMCID: PMC8786205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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