Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 targets the lysosome to mediate airway inflammatory cell death

22 Jan 2022

Abstract excerpt

As the coronavirus disease 2019 (COVID-19) pandemic continues to wreak havoc, researchers around the globe are working together to understand how the responsible agent - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) damages the respiratory system and other organs. Macroautophagy/autophagy is an innate immune response against viral infection and is known to be manipulated by positive-strand RNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium signaling and nucleotide metabolism
Share to Dermatological and COVID-19 studies
Share to Inflammasome and immune disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35067165
DOI: 10.1080/15548627.2021.2021496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

SARS-CoV-2 targets the lysosome to mediate airway inflammatory cell deathPMID 35067165Read ↗

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 InfectionSemantic proximity Read ↗

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 InfectionSemantic proximity Read ↗

Autophagy and inflammation in chronic respiratory disease.Semantic proximity Read ↗

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?Semantic proximity Read ↗

IL-1b drives SARS-CoV-2 disease in vivo, independently of the inflammasome and pyroptotic signallingSemantic proximity Read ↗

IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signallingSemantic proximity Read ↗

Autophagy Regulates Interferon Signaling to Control SARS-CoV-2 InfectionSemantic proximity Read ↗

SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosisSemantic proximity Read ↗

ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infectionSemantic proximity Read ↗

SARS-CoV-2 NSP6 reduces autophagosome size and affects viral replication via sigma-1 receptorSemantic proximity Read ↗

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.