Article

Autophagy Regulates Interferon Signaling to Control SARS-CoV-2 Infection

2023-01-24

Abstract excerpt

SummarySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in 2019 and has caused a massive pandemic, in part due to its ability to evade early recognition and innate immune defenses. In respiratory cells, SARS-CoV-2-dependent activation of interferons occurs not in infected cells, but rather in uninfected bystander cells. We set out to uncover mechanisms involved in controlling these early innate...

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Literature Corpus work: 75508986-71c9-528d-bf46-e697087eab05
DOI: 10.2139/ssrn.4330686

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