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ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection

13 Sept 2022

Abstract excerpt

Extracellular vesicles of endosomal origin, exosomes, mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Their diagnostic and therapeutic potential has been recognized for diseases such as cancer in which signaling defects are prominent. However, it is unclear to what extent exosomes and their cargo inform the progression of...

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PMID: 36099266
DOI: 10.1371/journal.pbio.3001754

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