Article
Early Onset Colorectal Cancer: Molecular Underpinnings Accelerating Occurrence.
Cellular and molecular gastroenterology and hepatology - 1 Jan 2025
Zinkeng Atehkeng, Taylor F Lloyd, Cheong Samuel H, Song Heyu, Merchant Juanita L
Abstract excerpt
The onset of colorectal cancer (CRC) in patients younger than 50 continues to rapidly increase. This study highlights the epidemiologic changes, risk factors, clinical characteristics, and molecular profiles prevalent in early onset CRC patients, and identifies key areas for future research. It has been noted that only a small fraction of early onset CRC cases is attributed to known hereditary mutations and fit...
Read the complete abstract on PubMedTopics
- Humans
- Colorectal Neoplasms
- Age of Onset
- Risk Factors
- Epigenesis, Genetic
- Polymorphism, Single Nucleotide