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EGFR Exon 20 Insertion Mutations in Sinonasal Squamous Cell Carcinoma

13 Jan 2022

Abstract excerpt

Recurrent epidermal growth factor receptor (EGFR)-activating mutations have been identified in a rare form of head and neck cancer known as sinonasal squamous cell carcinoma (SNSCC), a malignant disease with a 5-year mortality rate of ~40%. Interestingly, the majority of EGFR mutations identified in patients with primary SNSCC are exon 20 insertions (Ex20ins), which is in contrast to non-small-cell lung cancer...

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PMID: 35053553
DOI: 10.3390/cancers14020394

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