Article
The state of the art of EGFR exon 20 insertions in non-small cell lung cancer: Diagnosis and future perspectives.
Cancer treatment reviews - 1 Mar 2024
Dorta-Suárez Miriam, de Miguel Maria, Amor-Carro Oscar, Calderón José Miguel, González-Ortega MCarmen, Rodríguez-Abreu Delvys
Abstract excerpt
Insertions in the epidermal growth factor receptor (EGFR) exon 20 (Ex20Ins) are the third most incident mutations in non-small cell lung cancer (NSCLC). The hypervariable nature of these driver mutations hinders their identification by traditional polymerase chain reaction (PCR)-based methods, requiring a comprehensive sequencing approach to detect all possible insertions. The prognosis of patients with EGFR...
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