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Article

Targeting EGFR Exon 20 Insertion Mutations in Non-small-Cell Lung Cancer: Changes in Treatment Strategies are Coming.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Liu Haoli, Qin Jing, Qian Xinyu

Abstract excerpt

Epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations are the third most frequent EGFR mutation type, following only exon 19 deletions and exon 21 L858R point mutations. EGFR ex20ins mutations are found in approximately 4%-12% of all EGFR-positive non-small cell lung cancers (NSCLCs). Unlike classical EGFR mutations, EGFR ex20ins mutations display remarkable subtype diversity and...

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Identifiers

PMID: 39417568
DOI: 10.1177/10732748241292782
PMCID: PMC11489933

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