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Article

Clinical findings and prevalence of the mutation associated with primary ciliary dyskinesia in Old English Sheepdogs.

Journal of veterinary internal medicine - 1 Jan 2000

Merveille A-C, Battaille G, Billen F, Deleuze S, Fredholm M, Thomas A, Clercx C, Lequarré A-S

Abstract excerpt

BACKGROUND: Primary ciliary dyskinesia (PCD) is generally a recessively inherited disorder characterized by dysfunction of motile cilia. A mutation in a new causative gene (CCDC39) has been identified in the Old English Sheepdog (OES). OBJECTIVES: To describe the clinical findings and the molecular changes of affected dogs and estimate the worldwide prevalence of the mutation in a large cohort of OES. ANIMALS:...

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Cytoskeletal Proteins
Dog Diseases
Dogs
Genotyping Techniques
Kartagener Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24773602
DOI: 10.1111/jvim.12336
PMCID: PMC4895470

Genes

CCDC39

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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