Article

Anterior cingulate cortex hypofunction causes anti-social aggression in mice

2020-10-08

Abstract excerpt

Controlling aggression is a crucial skill in social species like rodents and humans, and has been associated with anterior cingulate cortex (ACC). Here, we demonstrate a causal link between ACC hypofunction and failed aggression control in BALB/cJ mice. We first show that ACC in BALB/cJ mice is structurally degraded: Neuron density is decreased, with pervasive neuron death and neuro-toxic astroglia. Gene-set enric...

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Literature Corpus work: a08cad6a-9f7b-52ba-9ebd-89813b96052c
DOI: 10.1101/2020.10.07.328765

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