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Article

A multi-omic analysis of the dorsal striatum in an animal model of divergent genetic risk for alcohol use disorder.

Journal of neurochemistry - 1 May 2021

Grecco Gregory G, Haggerty David L, Doud Emma H, Fritz Brandon M, Yin Fuqin, Hoffman Hunter, Mosley Amber L, Simpson Edward, Liu Yunlong, Baucum Anthony J, Atwood Brady K

Abstract excerpt

The development of selectively bred high and low alcohol-preferring mice (HAP and LAP, respectively) has allowed for an assessment of the polygenetic risk for pathological alcohol consumption and phenotypes associated with alcohol use disorder (AUD). Accumulating evidence indicates that the dorsal striatum (DS) is a central node in the neurocircuitry underlying addictive processes. Therefore, knowledge of...

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Identifiers

PMID: 33111353
DOI: 10.1111/jnc.15226
PMCID: PMC8076345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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