Article
Aldehyde dehydrogenase 2 gene rs671 G>A polymorphism is associated with an increased risk of digestive tract cancer.
The Journal of international medical research - 1 Oct 2023
Yang Yang, Liang Qun, Chen Yijin, Cao Yu, Zhuo Qingqing, Liu Boying, Wang Shengbing
Abstract excerpt
OBJECTIVE: Acetaldehyde can accumulate in cells and form acetaldehyde-DNA adducts that result in digestive tract cancer development. Acetaldehyde dehydrogenase 2 (ALDH2) enzymatic activity is involved in this process. Here, we aimed to analyze the relationship between an ALDH2 gene polymorphism and the digestive tract cancer risk in the Hakka population in China. METHODS: This was a retrospective study, with the...
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