Article
Evolution enhances mutational robustness and suppresses the emergence of a new phenotype: A new computational approach for studying evolution.
PLoS computational biology - 1 Jan 2022
Kaneko Tadamune, Kikuchi Macoto
Abstract excerpt
The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of mutational robustness and bistability. Living systems have developed their functions through evolutionary processes. To understand the particularities of this process theoretically,...
Topics
- Computational Biology
- Computer Simulation
- Evolution, Molecular
- Gene Regulatory Networks
- Genetic Fitness
- Models, Genetic
- Monte Carlo Method
- Mutation
- Phenotype
- Selection, Genetic
