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Article

Bistability, epigenetics, and bet-hedging in bacteria.

Annual review of microbiology - 1 Jan 2008

Veening Jan-Willem, Smits Wiep Klaas, Kuipers Oscar P

Abstract excerpt

Clonal populations of microbial cells often show a high degree of phenotypic variability under homogeneous conditions. Stochastic fluctuations in the cellular components that determine cellular states can cause two distinct subpopulations, a property called bistability. Phenotypic heterogeneity can be readily obtained by interlinking multiple gene regulatory pathways, effectively resulting in a genetic logic-AND...

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PMID: 18537474
DOI: 10.1146/annurev.micro.62.081307.163002

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