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Article

Contribution of RNA-RNA Interactions Mediated by the Genome Packaging Signals for the Selective Genome Packaging of Influenza A Virus.

Journal of virology - 23 Mar 2022

Miyamoto Sho, Muramoto Yukiko, Shindo Keiko, Fujita-Fujiharu Yoko, Morikawa Takeshi, Tamura Ryoma, Gilmore Jamie L, Nakano Masahiro, Noda Takeshi

Abstract excerpt

The influenza A virus genome is composed of eight single-stranded negative-sense viral RNA segments (vRNAs). The eight vRNAs are selectively packaged into each progeny virion. This process likely involves specific interactions between the vRNAs via segment-specific packaging signals located in both the 3'- and 5'-terminal regions of the respective vRNAs. To assess the importance of vRNA-vRNA interactions via...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35044211
DOI: 10.1128/JVI.01641-21
PMCID: PMC8941900

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