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Moving On Out: Transport and Packaging of Influenza Viral RNA into Virions

29 Sept 2016

Abstract excerpt

Influenza A viruses bear an eight-segmented single-stranded negative-sense RNA genome that is replicated in the nucleus. Newly synthesized viral RNA (vRNA) segments are exported from the nucleus and transported to the plasma membrane for packaging into progeny virions. Influenza viruses exploit many host proteins during these events, and this is the portion of the viral life cycle when genetic reassortment among...

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PMID: 27741407
DOI: 10.1146/annurev-virology-110615-042345

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