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Article

Packaging signal of influenza A virus

17 Feb 2021

Abstract excerpt

Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) segments are incorporated into virions in a selective manner. Evidence suggested that the highly selective genome packaging mechanism relies on RNA-RNA or protein-RNA interactions. The specific structures of each vRNA that contribute to...

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PMID: 33596956
DOI: 10.1186/s12985-021-01504-4

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