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Article

Rewiring the RNAs of influenza virus to prevent reassortment.

Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2009

Gao Qinshan, Palese Peter

Abstract excerpt

Influenza viruses contain segmented, negative-strand RNA genomes. Genome segmentation facilitates reassortment between different influenza virus strains infecting the same cell. This phenomenon results in the rapid exchange of RNA segments. In this study, we have developed a method to prevent the free reassortment of influenza A virus RNAs by rewiring their packaging signals. Specific packaging signals for...

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Identifiers

PMID: 19805230
DOI: 10.1073/pnas.0908897106
PMCID: PMC2747214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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