Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A conserved influenza A virus nucleoprotein code controls specific viral genome packaging.

Nature communications - 21 Sept 2016

Moreira Étori Aguiar, Weber Anna, Bolte Hardin, Kolesnikova Larissa, Giese Sebastian, Lakdawala Seema, Beer Martin, Zimmer Gert, García-Sastre Adolfo, Schwemmle Martin, Juozapaitis Mindaugas

Abstract excerpt

Packaging of the eight genomic RNA segments of influenza A viruses (IAV) into viral particles is coordinated by segment-specific packaging sequences. How the packaging signals regulate the specific incorporation of each RNA segment into virions and whether other viral or host factors are involved in this process is unknown. Here, we show that distinct amino acids of the viral nucleoprotein (NP) are required for...

Topics

Join the communities discussing this publication.

Chiroptera
Conserved Sequence
Genome, Viral
Models, Molecular
Nucleoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Orthomyxoviridae

Protein Conformation

Source

Open in PubMed Open full text

Identifiers

PMID: 27650413
DOI: 10.1038/ncomms12861
PMCID: PMC5035998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A conserved influenza A virus nucleoprotein code controls specific viral genome packaging.PMID 27650413Read ↗

Functionality of IAV packaging signals depends on site-specific charges within the viral nucleoprotein.Semantic proximity Read ↗

Packaging of the Influenza Virus Genome Is Governed by a Plastic Network of RNA- and Nucleoprotein-Mediated InteractionsSemantic proximity Read ↗

Disruption of the local vRNA structure at the end of HA encoding region interferes with the selective packaging of influenza A virus genome.Semantic proximity Read ↗

Packaging signal of influenza A virusSemantic proximity Read ↗

Contribution of RNA-RNA Interactions Mediated by the Genome Packaging Signals for the Selective Genome Packaging of Influenza A Virus.Semantic proximity Read ↗

The influenza A virus genome packaging network — complex, flexible and yet unsolvedSemantic proximity Read ↗

Selective flexible packaging pathways of the segmented genome of influenza A virusSemantic proximity Read ↗

An in vitro network of intermolecular interactions between viral RNA segments of an avian H5N2 influenza A virus: comparison with a human H3N2 virusSemantic proximity Read ↗

The structure of the influenza A virus genomeSemantic proximity Read ↗

Characterisation of influenza A viruses with mutations in segment 5 packaging signals.Semantic proximity Read ↗

Codon conservation in the influenza A virus genome defines RNA packaging signals.Semantic proximity Read ↗

Identification and targeting of a pan-genotypic influenza A virus RNA structure that mediates packaging and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.