Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of the local vRNA structure at the end of HA encoding region interferes with the selective packaging of influenza A virus genome.

Biochemical and biophysical research communications - 8 Jan 2026

Hu Jing, Li Jianchao, You Wanling, Liu Long, Chen Hongying

Abstract excerpt

Influenza A virus (IAV) selectively packages eight distinct viral RNA (vRNA) segments into progeny virions through segment-specific packaging signals located in the noncoding regions and their adjacent coding sequences. Emerging evidence indicates that local secondary structures within these regions are involved in intersegment RNA-RNA interactions required for selective genome incorporation. Here, we examined a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dogs
Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Madin Darby Canine Kidney Cells

Share to Nucleic Acid Conformation

Share to Orthomyxoviridae Infections

Share to Virus Assembly

Share to Virus Replication

Source

Identifiers

PMID: 41351899
DOI: 10.1016/j.bbrc.2025.153082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of the local vRNA structure at the end of HA encoding region interferes with the selective packaging of influenza A virus genome.PMID 41351899Read ↗

A conserved influenza A virus nucleoprotein code controls specific viral genome packaging.Semantic proximity Read ↗

The structure of the influenza A virus genomeSemantic proximity Read ↗

Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replicationSemantic proximity Read ↗

Contribution of RNA-RNA Interactions Mediated by the Genome Packaging Signals for the Selective Genome Packaging of Influenza A Virus.Semantic proximity Read ↗

Selective flexible packaging pathways of the segmented genome of influenza A virusSemantic proximity Read ↗

Influenza A virus defective viral genomes are inefficiently packaged into virions relative to wild-type genomic RNAsSemantic proximity Read ↗

New insights into the nonconserved noncoding region of the subtype-determinant hemagglutinin and neuraminidase segments of influenza A viruses.Semantic proximity Read ↗

Packaging of the Influenza Virus Genome Is Governed by a Plastic Network of RNA- and Nucleoprotein-Mediated InteractionsSemantic proximity Read ↗

Functionality of IAV packaging signals depends on site-specific charges within the viral nucleoprotein.Semantic proximity Read ↗

Moving On Out: Transport and Packaging of Influenza Viral RNA into VirionsSemantic proximity Read ↗

The influenza A virus genome packaging network — complex, flexible and yet unsolvedSemantic proximity Read ↗

Packaging signal of influenza A virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.