Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity

17 Jan 2022

Abstract excerpt

Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor Poly [ADP-ribose] polymerase 1 (PARP1) binds the EBV genome, stabilizes CTCF binding at specific loci, and that PARP1 enzymatic activity correlates with maintaining a transcriptionally active latency program. To better understand PARP1's role in regulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Plant Virus Research Studies
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35039491
DOI: 10.1038/s41467-021-27894-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activityPMID 35039491Read ↗

The three-dimensional structure of the EBV genome plays a crucial role in regulating viral gene expression in EBVaGCSemantic proximity Read ↗

PARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency TypeSemantic proximity Read ↗

PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoterSemantic proximity Read ↗

Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral InfectionSemantic proximity Read ↗

Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1Semantic proximity Read ↗

Interpreting the Epstein-Barr Virus (EBV) Epigenome Using High-Throughput DataSemantic proximity Read ↗

The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivationSemantic proximity Read ↗

Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid CellsSemantic proximity Read ↗

Landscape of the Epstein-Barr virus-host chromatin interactome and gene regulationSemantic proximity Read ↗

Histone loaders CAF1 and HIRA restrict Epstein-Barr virus B-cell lytic reactivationSemantic proximity Read ↗

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during ReactivationSemantic proximity Read ↗

A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.