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Article

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation

15 Nov 2017

Abstract excerpt

ABSTRACT The human genome is structurally organized in three-dimensional space to facilitate functional partitioning of transcription. We learned that the latent episome of the human Epstein-Barr virus (EBV) preferentially associates with gene-poor chromosomes and avoids gene-rich chromosomes. Kaposi's sarcoma-associated herpesvirus behaves similarly, but human papillomavirus does not. Contacts on the EBV side...

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PMID: 29142137
DOI: 10.1128/jvi.01413-17

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