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Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection

29 Apr 2023

Abstract excerpt

Epstein-Barr Virus (EBV) is a human gamma-herpesvirus that is widespread worldwide. To this day, about 200,000 cancer cases per year are attributed to EBV infection. EBV is capable of infecting both B cells and epithelial cells. Upon entry, viral DNA reaches the nucleus and undergoes a process of circularization and chromatinization and establishes a latent lifelong infection in host cells. There are different...

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PMID: 37243174
DOI: 10.3390/v15051088

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