Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells

29 Sept 2020

Abstract excerpt

, EBV can transform primary human B lymphocytes into immortalized cell lines. EBV-encoded proteins, along with noncoding RNAs and microRNAs, hijack cellular proteins and pathways to control cell growth. EBV nuclear proteins usurp normal transcriptional programs to activate the expression of key oncogenes, including MYC, to provide a proliferation signal. EBV nuclear antigens also repress CDKN2A to suppress...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Lymphoma Diagnosis and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32999023
DOI: 10.1128/jvi.01390-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid CellsPMID 32999023Read ↗

EBV Latency Programs: Molecular and Epigenetic Regulation and Its Role in Disease PathogenesisSemantic proximity Read ↗

HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr VirusSemantic proximity Read ↗

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during ReactivationSemantic proximity Read ↗

The Epstein-Barr Virus Enhancer Interaction Landscapes in Virus-Associated Cancer Cell LinesSemantic proximity Read ↗

The three-dimensional structure of the EBV genome plays a crucial role in regulating viral gene expression in EBVaGCSemantic proximity Read ↗

The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivationSemantic proximity Read ↗

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivationSemantic proximity Read ↗

Epstein–Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexesSemantic proximity Read ↗

Identification of <i>MEF2B</i> , <i>EBF1</i> , and <i>IL6R</i> as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte SurvivalSemantic proximity Read ↗

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivationSemantic proximity Read ↗

Landscape of the Epstein-Barr virus-host chromatin interactome and gene regulationSemantic proximity Read ↗

RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B LymphocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.