Article
Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas).
Journal of clinical pathology - 1 Jul 2023
Wells Kirsty, Lamrca Angela, Papaxoinis George, Wallace Andrew, Quinn Anne Marie, Summers Yvonne, Nonaka Daisuke
Abstract excerpt
AIM: Recent study has revealed frequent GTF2I mutation in thymomas, with the frequency being highest in types A and AB, followed by B1, B2, B3 and thymic carcinoma. This has led to the conclusion that GTF2I mutation correlates with more indolent histology subtype and better prognosis. In our study, the GTF2I mutation was tested in thymic epithelial tumours to investigate the relation between the mutation status...
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