Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical analysis of thyroid transcription factor-1 in type A and AB thymomas comparing multiple primary antibody clones.

Cancer treatment and research communications - 1 Jan 2025

Mitsui Ayaka, Kashima Jumpei, Kishikawa Satsuki, Watanabe Shun-Ichi, Goto Yasushi, Yatabe Yasushi

Abstract excerpt

Thyroid transcription factor-1 (TTF-1) is expressed in the thyroid gland, lungs, and brain, and has also been reported in thymomas. While some studies have suggested TTF-1 as a specific marker for type AB thymoma, others have noted significant variability, often due to small case numbers. In this study, TTF-1 expression was evaluated in 50 cases of type A and AB thymomas using three distinct clones (8G7G3/1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Thymoma

Share to Thymus Neoplasms

Share to Thyroid Nuclear Factor 1

Share to Transcription Factors

Share to Transcription Factors, TFII

Source

Identifiers

PMID: 41317642
DOI: 10.1016/j.ctarc.2025.101045

Genes

GTF2I

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical analysis of thyroid transcription factor-1 in type A and AB thymomas comparing multiple primary antibody clones.PMID 41317642Read ↗

Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas).Semantic proximity Read ↗

Constant p.L424H Mutation in GTF2I in Micronodular Thymomas With Lymphoid Stroma: Evidence Supporting Close Relationship With Type A and AB Thymomas.Semantic proximity Read ↗

Molecular pathology of thymomas: implications for diagnosis and therapy.Semantic proximity Read ↗

Type AB thymoma is not a mixed tumor of type A and type B thymomas, but a distinct type of thymoma.Semantic proximity Read ↗

Immunological presentations and clinical features associated with Thymic Malignancies: The potential role of histological classifications and tumour grading on the future recurrence of opportunistic infections and paraneoplastic autoimmune conditionsSemantic proximity Read ↗

Immunohistochemical Evaluation of T Cell Receptor and T Cell Receptor Beta Constant 1 Expression Distinguishes Benign and Neoplastic Immature T Cell Populations and Reveals Discrete TRBC1/TCR PhenotypesSemantic proximity Read ↗

Deciphering the biology of thymic epithelial tumorsSemantic proximity Read ↗

Significance of YAP1-MAML2 rearrangement and GTF2I mutation in the diagnosis and differential diagnosis of metaplastic thymoma.Semantic proximity Read ↗

GTF2I mutation in micronodular thymoma with lymphoid stroma.Semantic proximity Read ↗

The Integrated Genomic Landscape of Thymic Epithelial Tumors.Semantic proximity Read ↗

Thymic Adenocarcinoma with Positivity for Thyroid Transcription Factor-1 and a BRAF V600E Mutation.Semantic proximity Read ↗

Primary Driver Mutations in GTF2I Specific to the Development of ThymomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.