Article
DNA Methylation and Age-Independent Cardiovascular Risk, an Epigenome-Wide Approach: The REGICOR Study (REgistre GIroní del COR).
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2018
Fernández-Sanlés Alba, Sayols-Baixeras Sergi, Curcio Santiago, Subirana Isaac, Marrugat Jaume, Elosua Roberto
Abstract excerpt
OBJECTIVE: The objectives of this study were to decipher whether age-independent cardiovascular risk is associated with DNA methylation at 5'-cytosine-phosphate-guanine-3' (CpG) level and to determine whether these differential methylation signatures are associated with the incidence of cardiovascular events. APPROACH AND RESULTS: We designed a 2-stage, cross-sectional, epigenome-wide association study....
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