Article

Multi-ancestry genome-wide analysis identifies effector genes and druggable pathways for coronary artery calcification

2022-05-05

Abstract excerpt

Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts symptomatic coronary artery disease. Identifying genetic risk factors for CAC may point to new therapeutic avenues for preventing clinical disease. Here, we conducted a multi-ancestry genome-wide association study in 26,909 individuals of European ancestry and 8,867 individuals of African American ancestry. We identified 11 ind...

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Literature Corpus work: 1d5e1731-d390-5659-b6c0-db221aa986ea
DOI: 10.1101/2022.05.02.22273844

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