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Article

The Role and Mechanism of SIRT6 in Regulating Phenotype Transformation of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm.

Computational and mathematical methods in medicine - 1 Jan 2022

Guan Xiaomei, Xin Hai, Xu Meiling, Ji Jianlei, Li Jun

Abstract excerpt

BACKGROUND: Data mining of current gene expression databases has not been previously performed to determine whether sirtuin 6 (SIRT6) expression participates in the pathological process of abdominal aortic aneurysm (AAA). The present study was aimed at investigating the role and mechanism of SIRT6 in regulating phenotype transformation of vascular smooth muscle cells (VSMC) in AAA. METHODS: Three gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35035519
DOI: 10.1155/2022/3200798
PMCID: PMC8758316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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