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Article

Analysis of genetic variants in myeloproliferative neoplasms using a 22-gene next-generation sequencing panel.

BMC medical genomics - 15 Jan 2022

Tan Jaymi, Chow Yock Ping, Zainul Abidin Norziha, Chang Kian Meng, Selvaratnam Veena, Tumian Nor Rafeah, Poh Yang Ming, Veerakumarasivam Abhi, Laffan Michael Arthur, Wong Chieh Lee

Abstract excerpt

BACKGROUND: The Philadelphia (Ph)-negative myeloproliferative neoplasms (MPNs), namely essential thrombocythaemia (ET), polycythaemia vera (PV) and primary myelofibrosis (PMF), are a group of chronic clonal haematopoietic disorders that have the propensity to advance into bone marrow failure or acute myeloid leukaemia; often resulting in fatality. Although driver mutations have been identified in these MPNs,...

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Identifiers

PMID: 35033063
DOI: 10.1186/s12920-021-01145-0
PMCID: PMC8760696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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