Article

Analysis of Genetic Variants in Myeloproliferative Neoplasms Using a 22-Gene Next-Generation Sequencing Panel

2021-08-19

Abstract excerpt

<h4>Background: </h4> The Philadelphia (Ph)-negative myeloproliferative neoplasms (MPNs) (i.e. essential thrombocythaemia (ET), polycythaemia vera (PV), and primary myelofibrosis (PMF)) are a group of chronic clonal haematopoietic disorders that have the propensity to advance into bone marrow failure or acute myeloid leukaemia; often resulting in fatality. Although driver mutations have been identified in these Ph...

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Literature Corpus work: 30149b09-e088-5e72-b2e7-42554c670dd0
DOI: 10.21203/rs.3.rs-721996/v1

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