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Article

Sequential analysis of 18 genes in polycythemia vera and essential thrombocythemia reveals an association between mutational status and clinical outcome.

Genes, chromosomes & cancer - 1 May 2017

Luque Paz Damien, Chauveau Aurélie, Boyer Françoise, Buors Caroline, Samaison Laura, Cottin Laurane, Seegers Valérie, Férec Claude, Le Maréchal Cédric, Gueguen Paul, Lippert Eric, Ianotto Jean-Christophe, Ugo Valérie

Abstract excerpt

Philadelphia-negative classical myeloproliferative neoplasms (MPN) are clonal diseases characterized by driver mutations of JAK2, MPL, or CALR. Additional mutations may occur in epigenetic regulators, signaling, or splicing genes that may be useful in the prognostic assessment of MPN patients. In primary myelofibrosis, molecular-based prognostic scoring systems have been recently proposed, but few data are...

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Source

Identifiers

PMID: 27997717
DOI: 10.1002/gcc.22437

Genes

CALR
JAK2
MPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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