Article

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

2021-09-29

Abstract excerpt

As the coronavirus disease 2019 (COVID-19) pandemic continues, there is a strong need for highly potent monoclonal antibodies (mAbs) that are resistant against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VoCs). Here, we evaluate the potency of a previously described mAb J08 against these variants using cell-based assays and delve into the molecular details of the binding inter...

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Literature Corpus work: 3612a5aa-cfee-5ba2-b053-7ff7c303c27b
DOI: 10.1101/2021.09.28.462234

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