Article
TNF-α response in macrophages depends on clinical Legionella pneumophila isolates genotypes.
Virulence - 1 Dec 2022
Guillemot Johann, Ginevra Christophe, Allam Camille, Kay Elisabeth, Gilbert Christophe, Doublet Patricia, Jarraud Sophie, Chapalain Annelise
Abstract excerpt
Legionnaires' Disease (LD) is a severe pneumonia mainly caused in Europe by Legionella pneumophila serogroup 1 (Lp1). Sequence-based typing methods reveal that some sequence types (ST) are overrepresented in clinical samples such as ST1 and ST47, suggesting that some strains are more fit for infection than others. In the present study, a collection of 108 Lp1 clinical isolates were used to evaluate the...
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