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Transcriptome analysis of infected human macrophages between strains of Brucella melitensis and an omp31 mutant.

Cellular and molecular biology (Noisy-le-Grand, France) - 24 Nov 2024

Queijeiro-Barroso Cloé, Ramírez-Salcedo Jorge, Méndez-Alemán Julio M, Puente-García José L, Verdiguel-Fernández Lázaro F, Verdugo-Rodríguez Antonio

Abstract excerpt

Brucella spp. are small aerobes non-motile Gram-negative coccobacilli that act as facultative intracellular pathogens responsible for zoonotic infections. B. melitensis can survive and replicate within host macrophages, the molecular phenomena of this host: pathogen interaction remain totally unknown. The aim of this work was to evaluate the differences in the response between human macrophages infected with...

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PMID: 39605129
DOI: 10.14715/cmb/2024.70.10.2

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