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Article

Pathways of IL-1β secretion by macrophages infected with clinical Mycobacterium tuberculosis strains.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2013

Krishnan Nitya, Robertson Brian D, Thwaites Guy

Abstract excerpt

The pro-inflammatory cytokine IL-1β is a key mediator of inflammation and plays an important role in the host resistance to Mycobacterium tuberculosis infections. To date, most studies have examined the mechanisms of IL-1β secretion using laboratory strains of M. tuberculosis and the findings may not be widely applicable to contemporary clinical strains. Here, we investigated the primary pathways of IL-1β...

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Identifiers

PMID: 23849220
DOI: 10.1016/j.tube.2013.05.002
PMCID: PMC3759846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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