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Article

Drug resistant clinical isolates of Mycobacterium tuberculosis from different genotypes exhibit differential host responses in THP-1 cells.

PloS one - 1 Jan 2013

Chakraborty Pampi, Kulkarni Savita, Rajan Ramakrishna, Sainis Krishna

Abstract excerpt

Mycobacterium tuberculosis (MTB) persistently infects and survives within the host macrophages. Substantial genotypic variation exists among MTB strains which correlate with their interactions with the host. The present study was designed to establish a correlation, if any, between infection and induction of innate immune response by genetically diverse drug resistant MTB isolates from India. For this purpose,...

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Identifiers

PMID: 23667550
DOI: 10.1371/journal.pone.0062966
PMCID: PMC3646887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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