Article
CEST MRI provides amide/amine surrogate biomarkers for treatment-naïve glioma sub-typing.
European journal of nuclear medicine and molecular imaging - 1 Jun 2022
Mancini Laura, Casagranda Stefano, Gautier Guillaume, Peter Philippe, Lopez Bruno, Thorne Lewis, McEvoy Andrew, Miserocchi Anna, Samandouras George, Kitchen Neil, Brandner Sebastian, De Vita Enrico, Torrealdea Francisco, Rega Marilena, Schmitt Benjamin, Liebig Patrick, Sanverdi Eser, Golay Xavier, Bisdas Sotirios
Abstract excerpt
PURPOSE: Accurate glioma classification affects patient management and is challenging on non- or low-enhancing gliomas. This study investigated the clinical value of different chemical exchange saturation transfer (CEST) metrics for glioma classification and assessed the diagnostic effect of the presence of abundant fluid in glioma subpopulations. METHODS: Forty-five treatment-naïve glioma patients with known...
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