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Article

Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study.

Scientific reports - 17 Jul 2020

Yao Jingwen, Hagiwara Akifumi, Raymond Catalina, Shabani Soroush, Pope Whitney B, Salamon Noriko, Lai Albert, Ji Matthew, Nghiemphu Phioanh L, Liau Linda M, Cloughesy Timothy F, Ellingson Benjamin M

Abstract excerpt

Co-deletion of 1p/19q is a hallmark of oligodendroglioma and predicts better survival. However, little is understood about its metabolic characteristics. In this study, we aimed to explore the extracellular acidity of WHO grade II and III gliomas associated with 1p/19q co-deletion. We included 76 glioma patients who received amine chemical exchange saturation transfer (CEST) imaging at 3 T. Magnetic transfer...

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Identifiers

PMID: 32681084
DOI: 10.1038/s41598-020-68733-5
PMCID: PMC7367867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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