Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T.

doi:10.1093/neuonc/noy073

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Article

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T.

Neuro-oncology - 12 Nov 2018

Paech Daniel, Windschuh Johannes, Oberhollenzer Johanna, Dreher Constantin, Sahm Felix, Meissner Jan-Eric, Goerke Steffen, Schuenke Patrick, Zaiss Moritz, Regnery Sebastian, Bickelhaupt Sebastian, Bäumer Philipp, Bendszus Martin, Wick Wolfgang, Unterberg Andreas, Bachert Peter, Ladd Mark Edward, Schlemmer Heinz-Peter, Radbruch Alexander

Abstract excerpt

Background: Early identification of prognostic superior characteristics in glioma patients such as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status is of great clinical importance. The study purpose was to investigate the non-invasive predictability of IDH mutation status, MGMT promoter methylation, and differentiation of low-grade versus...

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Identifiers

PMID: 29733378
DOI: 10.1093/neuonc/noy073
PMCID: PMC6231210

Genes

MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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