Article
Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI.
Magnetic resonance in medicine - 1 Sept 2017
Jiang Shanshan, Zou Tianyu, Eberhart Charles G, Villalobos Maria A V, Heo Hye-Young, Zhang Yi, Wang Yu, Wang Xianlong, Yu Hao, Du Yongxing, van Zijl Peter C M, Wen Zhibo, Zhou Jinyuan
Abstract excerpt
PURPOSE: To assess the amide proton transfer-weighted (APTw) MRI features of isocitrate dehydrogenase (IDH)-wildtype and IDH-mutant grade II gliomas and to test the hypothesis that the APTw signal is a surrogate imaging marker for identifying IDH mutation status preoperatively. METHODS: Twenty-seven patients with pathologically confirmed low-grade glioma, who were previously scanned at 3T, were retrospectively...
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