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Article

Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014.

The journals of gerontology. Series A, Biological sciences and medical sciences - 12 Aug 2022

Ji John S, Liu Linxin, Zeng Yi, Yan Lijing L

Abstract excerpt

Forkhead Box O 3 (FOXO3) genotype is strongly associated with human longevity and may be protective against neurodegeneration. Air pollution is a risk factor for cognitive decline and dementia. We aimed to study the individual and combined effects of FOXO3 and air pollution on cognitive function in a large prospective cohort with up to 14 years of follow-up. We measured cognitive function and impairment using the...

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Identifiers

PMID: 35029671
DOI: 10.1093/gerona/glac016
PMCID: PMC9890624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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