Article
Air Pollution Control Mitigates Frailty Progression: Evidence from Two Cohorts of Older Adults and DNA Methylation Insights
12 May 2025
Abstract excerpt
Frailty is an underappreciated but modifiable clinical syndrome, but little about how air quality improvements could influence frailty progression is known. Here, we utilized two Chinese cohorts with repeated follow-up visits to address this knowledge gap and explored the underlying DNA methylation mechanisms. We first conducted a multistate modeling analysis in the Chinese Longitudinal Healthy Longevity Study...
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