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Article

Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan.

Environment international - 1 Mar 2020

Kulick Erin R, Elkind Mitchell S V, Boehme Amelia K, Joyce Nina R, Schupf Nicole, Kaufman Joel D, Mayeux Richard, Manly Jennifer J, Wellenius Gregory A

Abstract excerpt

BACKGROUND: There is mounting evidence that long-term exposure to air pollution is related to accelerated cognitive decline in aging populations. Factors that influence individual susceptibility remain largely unknown, but may involve the apolipoprotein E genotype E4 (APOE-ε4) allele. OBJECTIVES: We assessed whether the association between long-term exposure to ambient air pollution and cognitive decline differed...

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Identifiers

PMID: 31926436
DOI: 10.1016/j.envint.2019.105440
PMCID: PMC7024003

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