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Article

Exploring the effects of gene dosage on mandible shape in mice as a model for studying the genetic basis of natural variation.

Development genes and evolution - 1 Sept 2013

Boell Louis, Pallares Luisa F, Brodski Claude, Chen Yiping, Christian Jan L, Kousa Youssef A, Kuss Pia, Nelsen Sylvia, Novikov Orna, Schutte Brian C, Wang Ying, Tautz Diethard

Abstract excerpt

Mandible shape in the mouse is a complex trait that is influenced by many genetic factors. However, little is known about the action of single genes on adult mandible shape so far, since most developmentally relevant genes are already required during embryogenesis, i.e., knockouts lead to embryonic death or severe deformations, before the mandible is fully formed. We employ here a geometric morphometric approach...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23563729
DOI: 10.1007/s00427-013-0443-y
PMCID: PMC4013528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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